Sat 21 Nov 2009
OTHER EFFECTS OF ESTROGENS
In addition to the serious known risks of estrogens described above, estrogens have the following side effects and potential risks:
1. Nausea and vomiting. The most common side
effect of estrogen therapy is nausea. Vomiting is
less common.
2. Effects on breasts. Estrogens may cause
breast tenderness or enlargement and may cause
the breasts to secrete a liquid. These effects are not
dangerous.
3. Effects on the uterus. Estrogens may cause
benign fibroid tumors of the uterus to get larger.
Some women will have menstrual bleeding when estrogens are stopped for one week each month. But if the bleeding occurs on days you are still taking estrogens you should report this to your doctor.
4. Effects on liver. Women taking oral contra
ceptives develop on rare occasions a benign turnor
of the liver which can rupture and bleed into the
abdomen. So far, these tumors have not been re
ported in women using estrogens in the meno
pause, but you should report any swelling or un
usual pain or tenderness in the abdomen to your
doctor immediately.
Women with a past history of jaundice (yellowing of the skin and white parts of the eyes) may get jaundice again during estrogen use. If this occurs, stop taking estrogens and see your doctor.
5. Mental depression. A few women develop
depression while on estrogen therapy. If you have
had depression in the past, it may reappear or get
worse during estrogen therapy. If you do become
severely depressed, stop taking estrogens and call
your doctor.
6. Other effects. Estrogens may cause excess fluid to be retained in the body. This may make some conditions worse, such as epilepsy, migraine, heart disease, or kidney disease.
A spotty darkening of the skin can develop, particularly in the face, and may persist.
SUMMARY
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