Sat 21 Nov 2009
SINEMET (Levodopa, Carbidopa)Sinemet is used to treat some of the symptoms of Parkinson’s disease, such as tremor, rigidity, sluggish movements and disturbances when walking.
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SINEMET (Levodopa, Carbidopa)
INSTRUCTIONS
Sinemet is used to treat some of the symptoms of Parkinson’s disease, such as tremor, rigidity, sluggish movements and disturbances when walking. It is intended as an aid to reduce troublesome symptoms; it should not be expected to cure Parkinsonism.
Follow the instructions on the prescription exactly. Do not take a larger or smaller dose than the prescription tells you to. It is better to take Sinemet with meals or with food because it will be less likely to cause stomach irritation or nausea.
PRECAUTIONS
Using medications together may sometimes cause unfavorable reactions. So tell your doctor about any medicine you are taking now (including drugs you buy without prescription). This is especially true if you take medicine to treat high blood pressure (such asrnethyldopa [Aldomet] reserpine,andpargyline); MAO inhibitor drugs used as anlidepressants; other drugs for Parkinsonism such as Artane, Cogentin, Kemadrin and others; Haloperidol; Papaverine; Phenothiazides; Pyridox-ine (Vitamin B(i—be sure that any vitamin preparation you take does not contain pyridoxine because it may stop the beneficial action of Sinemet). Tell your doctor if you have been taking Sinemet alone (not in combination with Carbidopa) as this will affect your dosage schedule.
Tell your physician, before you start taking Sinemet, if you have diabetes, epilepsy, high blood pressure, heart, lung, liver or kidney disease, peptic ulcers, melanoma, or if you plan to have surgery with a general anesthetic while you take Sinemet.
POSSIBLE SIDE EFFECTS
Effective medicine may cause “side effects” in some people. New symptoms may be caused by the medicine, the original disorder or a new illness that may develop. Most people experience few or no side effects, and those that do happen tend to disappear in time after you stop using the medicine or when your body adjusts to it.
It is possible that Sinemet may cause emotional depression, confusion, abnormal behavior, unusual movements of the head or other parts of the body, “indigestion” or other symptoms of peptic ulcer, intestinal bleeding that may be discovered by vomiting blood or material that looks like coffee grounds or bowel movements that are black in color (some changes in the blood may be found only by laboratory blood tests in their early stages), fever, sore throat, skin discomfort, reduced appetite, headache, dizziness, blurred vision, heart
palpitations, difficulty in emptying your bladder, an odd taste in your mouth, offensive body odor and changes in sex drive. If you should develop any of these symptoms to an uncomfortable degree or think that the medicine is bothering you in some other way, stop taking it temporarily and notify your doctor. He may decide to change your dosage schedule or discontinue the medicine.
YOUR ACTIVITIES OF DAILY LIVING
Until you experience how this medicine
affects you, don’t drive a car or other
vehicle, don’t work around dangerous machinery, don’t climb ladders, and don’t work in high places. Especially follow these restrictions if you also drink any beverage with alcohol, or take any other medicine that might affect your alertness or reflexes, such as tranquilizers, sedatives, anti-histamines, medicine for pain, and others.
STORAGE
Keep this medicine in a tightly closed container in a dry, cool place away from heat or direci sunlight and out of reach of children. Don’t use the bathroom cabinet because humidity is high there. If you store medicine in the refrigerator, do not let it freeze. Don’t save left-over medicine to “use later.” Discard it on the expiration date shown on the container, but do so in a way that will protect children or pets-flush down the toilet, for example.
OVERDOSAGE: WHAT TO DO
CALL THE DOCTOR OR…
FOR HELP OR AN AMBULANCE. Then give FIRST AID!
The patient is unconscious or very drowsy: (a) Not breathing: Try mouth-lo-mouth breathing.
(b) No heart beat: Use cardiac massage if you know
how; hit the breast-bone hard with your fist.
(c) Don’t try to make him vomit, (d) If you can’t get
help, take the patient to the nearest qualified
Emergency facility.
The patient is alert: (a) Give milk (undiluted evaporated milk is best), (b) Try to induce vomiting with Syrup of Ipecac’ if available; otherwise push your finger far back in his throat. Try to save the vomit for tests. Next, give Activated Charcoal.” (c) If no professional help can be found, don’t wait. Take the patient to the nearest Emergency facility.
ALWAYS BRING ANY REMAINING MEDICINE AND EMPTY BOTTLES!
“Syrup of Ipecac and Activated Charcoal with instructions should be in every household for treatment of medication accidents. Ask your doctor for them.
Please post this information sheet in a conspicuous place close to where you store the medicine so you will see it frequently andean refer to it easily. To avoid future confusion with other medicines, discard this sheet when you finish the course of treatment requiring the use of this drug.